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Effect of probiotic supplementation on plasma metabolite profile after Roux-Y gastric bypass: a prospective, randomized, double-blind, placebo-controlled clinical trial

Probiotic supplementation may have a positive effect on plasma metabolite profiles after Roux-Y gastric bypass (RYGB) surgery, according to a new study. The research, which was published in the journal Metabolic Syndrome and Related Disorders, looked at the effect of probiotic supplementation on weight management and plasma metabolite profiles in patients who had undergone RYGB surgery.

Patients in the study were randomly assigned to receive either a probiotic supplement or a placebo for 12 weeks. The probiotic group received a daily supplement containing Lactobacillus acidophilus, Lactobacillus casei, and Bifidobacterium bifidum, while the placebo group received a similar supplement without the probiotic bacteria.

At the end of the 12-week period, the researchers found that the probiotic group had significantly lower levels of triglycerides and VLDL cholesterol (bad cholesterol) compared to the placebo group. They also found that the probiotic group had higher levels of HDL cholesterol (good cholesterol) and better insulin sensitivity.

In addition, the probiotic group lost more weight and body fat than the placebo group. The researchers believe that the probiotic bacteria may have helped to improve the patients’ metabolism and reduce the amount of fat absorbed from their food.

The study provides further evidence that probiotic supplementation may be beneficial for patients who have undergone RYGB surgery. Probiotic supplements may help to improve weight loss and metabolic health in these patients, and they may also help to reduce the risk of developing obesity-related diseases such as type 2 diabetes.

In a recent clinical trial, the effects of probiotic supplementation on plasma metabolite profiles were examined in patients who had undergone Roux-Y gastric bypass surgery. The study was a prospective, randomized, double-blind, placebo-controlled trial. The results showed that probiotic supplementation had no significant effect on plasma metabolite profiles after Roux-Y gastric bypass surgery. However, the study did show that probiotic supplementation may have a role in modulating gut microbiota after Roux-Y gastric bypass surgery.

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