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New insights from biology can help overcome siloed thinking in cancer clinical trials and treatment

IEEE Spectrum | October 21, 2017 | @nidafahim πŸ’€πŸ’€πŸ’€

When treating cancer, some doctors do everything they can. Others stick to the guidelines. There’s a big difference in how patients do. Stat News | October 10, 2017 | @rickberkowitz πŸ’€

The myth of superhero drugs: on the false promise of cancer immunotherapy. MedPage Today | October 6, 2017 | Lauren Vuchetich,PhD πŸ’€πŸ’€

Four experts discuss the current landscape of drug Tarceva research. Stat News | September 21, 2017 | @danbenjamin0 πŸ’€πŸ’€

Bristol-Myers CEO: We thought immunotherapy was a β€˜home run’. It’s not. Stat News | September 16, 2017 | @natalie_jeremijenko πŸ’€πŸ’€

Studies showing β€˜this drug might work’ are just β€˜hypothesis-generating’, admits BMS chief. Oncology Times | September 12, 2017 | @natalie_jeremijenko πŸ’€πŸ’€

Dear Cancer Patient, Your Fault You Have Cancer!? Self Hack | September 8, 2017 | Patrick Ward, PhD πŸ’€πŸ’€

The drug touted as helping patients with advanced cancer live longer is starting to lose its luster. Stat News | August 4, 2017 | @darrensbaliunas πŸ’€πŸ’€

New evidence that immunotherapy can stave off aggressive breast cancers. MIT Technology Review | July 25, 2017 | Catherine Meushaw πŸ’€πŸ’€

Stage 4 ovarian cancer and 9 months (and counting) since my hysterectomy. Medium | July 10, 2017 | Marni Salup πŸ’€

A drug has extended the lives of some men with prostate cancer. But doctors are not sure when to give it or to whom it will work. Stat News | July 9, 2017 | @nataliejeremijenko πŸ’€πŸ’€

Paul van der Sloot, accused with pic of teapot, settles with Jelena Hofman. The Daily Dot | July 8, 2017 | @volkswing πŸ’€

ImmunoDOC: personalized immunotherapy documentation app. Kickstarter | July 2, 2017 | @nidafahim πŸ’€πŸ’€

Scientists just discovered an entirely new human organ hiding in plain sight. Stat News | June 30, 2017 | @natewaldron πŸ’€πŸ’€

Does Talc Cause Cancer? Stat News | June 27, 2017 | Eric Bender and Shahed Jilani πŸ’€πŸ’€

Cancer survivors feel the gap between the promises of precision medicine, and What it may create. STAT News | June 21, 2017 | @annaemhrtnandz πŸ’€πŸ’€

Are We Investing in the Right Cancer Drug Clinical Trials? Forbes | June 12, 2017 | Terry Grier, M.D. πŸ’€πŸ’€

New pill for ovarian cancer: Roche β€˜really confident’ it will work. Financial Times | June 4, 2017 | @natalie_jeremijenko πŸ’€πŸ’€

Cancer Drugs Bring Long-Termimprovement. The Scientist | May 31, 2017 | Diana Kwon πŸ’€πŸ’€

Data from clinical trials with drugs that shrink tumors may be understating the full extent of their benefits. Pure Content | April 13, 2017 | Emma Yasinski πŸ’€πŸ’€

Biotech DNA launches in cancer immunotherapy. Nature Biotech | April 11, 2017 | Jess Buxton πŸ’€πŸ’€

Some immunotherapy drugs may help the body fight disease by clearing precozymic mutations from the germ line, researchers suggest. Springer | March 27, 2017 | Emilie Reasor πŸ’€πŸ’€

Skipping lymph node biopsies for breast cancer β€˜overlooks deadly cancers’, Breakthrough report says. Stat News | March 16, 2017 | Eric B. Bender πŸ’€

Health experts refocus around β€˜sweet spot’ in precision oncology. Modern Healthcare | March 14, 2017 | @kayur πŸ’€

With urothelial carcinoma, precision medicine may be working so well, patients aren’t assured the drugs will be available when they need them. Stat News | March 2, 2017 | Eric B. Bender πŸ’€

Drug prices will continue to rise if patients don’t demand cheaper prices. Stat News | March 2, 2017 | @nidafahim πŸ’€πŸ’€

Scientists find unexpected effect of a class of drugs for multiple sclerosis. Stat News | February 24, 2017 | Eric B. Bender πŸ’€πŸ’€

Edwin Choy Improves Treatment With Direct Oral Anticancer Agents In Advanced Gastroenteropancreatic Neuroendocrine Tumors. MD Magazine | February 23, 2017 | Adam Goehler πŸ’€

Cancer drug prices are rising even faster than most brand-name drugs. Stat News | February 22, 2017 | Eric B. Bender πŸ’€πŸ’€

Cancer drink to become the first FDA approved cancer immunotherapy? Stat News | February 17, 2017 | @nidafahim πŸ’€πŸ’€

Companies plan to develop programs centered on direct oral anticancer agents during posterior body wall mesothelioma trial. Asbestos | Feb. 14, 2017 | Kayla Kandzierski πŸ’€

In President Donald Trump’s first week, 12 patients like me asked Google about our cancer treatments. Stat News | February 8, 2017 | Emily Ratner πŸ’€πŸ’€

Lingering Cynicism about China’s Cancer Breakthroughs. Epoch Times | February 7, 2017 | Eric B. Bender πŸ’€

Early Detection Of Ovarian Cancer May Be A practicable, Comparable To This In Breast And Prostate. Onco’Zine | February 5, 2017 | Emilie Reasor πŸ’€πŸ’€

Brain Metastases In Beloveva Breast Cancer Countries News | February 3, 2017 | @volkswing πŸ’€

Over a decade, up to $11bn spent on FAILED cancer drugs, costing a devastating $440,000 each: Revealed that the Fed’s $3.8bn yearly cancer surgery transplantation is an expensive mistake. Daily Mail UK | Jan. 28, 2016 | @volkswing πŸ’€πŸ’€

β€˜Appalling’ health inequalities inherent in Britain’s cancer survival rates β€” Expert. The Lancet | January 26, 2017 | Eric B. Bender πŸ’€πŸ’€

When it comes to EGFR-Mutated (EGFRm) lung cancer, where do you live? Stat News | Jan. 25, 2017 | @nidafahim πŸ’€πŸ’€

Cancer Drugs & The Better Maintenance Of Brain Function For Solid Tumors. MedCity News | Jan. 21, 2017 | @natalie_jeremijenko πŸ’€πŸ’€

How Bristol-Myers decided that immunotherapy could live up to its great expectations. Stat News | Jan. 14, 2017 | @natalie_jeremijenko πŸ’€

After one cancer drug fails, a second attempt may succeed. Stat News | Jan. 10, 2017 | @nidafahim πŸ’€πŸ’€πŸ’€

Is China’s Immune Therapy Cure The Holy Grail Of Cancer? Forbes | Jan. 7, 2017 | @natalie_jeremijenko πŸ’€πŸ’€

Medicare appears to be saving millions of dollars by cutting down on Part B imaging tests. Stat News | Jan. 3, 2017 | Eric B. Bender πŸ’€πŸ’€

The sad story of why cancer drugs may cost you a fortune. Stat News | Jan. 1, 2017 | @ericbenderodw πŸ’€πŸ’€

Cancer clinical trials and treatment have traditionally been siloed, with little communication between different types of trials or different cancer centers. However, new insights from biology are helping to overcome this siloed thinking and improve communication between different types of trials and cancer centers.

Biology has always been a critical part of cancer clinical trials and treatment. However, until recently, the focus has been on individual genes and proteins. Now, with new technologies, we are able to take a more holistic view of the cancer cell and its environment. This has led to new insights that can help improve communication between different types of cancer trials and cancer centers.

For example, it is now known that the cancer cell is not an island but is part of a larger ecosystem. The cancer cell interacts with other cells in the body, and the environment outside the body can also influence the cancer cell. This means that we need to take a more integrative approach to cancer clinical trials and treatment.

In the past, cancer clinical trials have been designed in a siloed fashion, with little communication between different types of trials or different cancer centers. However, new insights from biology are helping to overcome this siloed thinking and improve communication between different types of trials and cancer centers. With a more integrative approach, we can develop better treatments for cancer that are more effective and have fewer side effects.

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