Scientists have found some key differences in how our immune system responds to two of the SARS-CoV-2 vaccines currently in use. The findings could help to explain why some people are more protected against the virus than others.
The two vaccines, manufactured by Pfizer/BioNTech and Moderna, use different approaches to stimulate our immune system to create antibodies against the SARS-CoV-2 virus. The Pfizer/BioNTech vaccine uses a piece of the virus’ genetic material (RNA) to trigger an immune response, while the Moderna vaccine uses a piece of DNA.
While both vaccines appear to be effective at inducing an immune response, the new study found that the Pfizer/BioNTech vaccine was better at stimulating production of so-called “memory” B cells. These are a type of white blood cell that remains in our body after exposure to a virus, ready to fight off any future infection.
The study also found that the Pfizer/BioNTech vaccine was better at inducing production of a type of antibody known as IgG3. This is the antibody that is most effective at neutralizing the SARS-CoV-2 virus.
The findings help to explain why the Pfizer/BioNTech vaccine appears to be more effective than the Moderna vaccine at preventing infection. They also suggest that the Pfizer/BioNTech vaccine may provide long-lasting protection against the virus.
A recent study has provided new insight into the key differences in immune response to SARS-CoV-2 vaccines.
The study, which was conducted by a team of researchers from the University of Washington School of Medicine, looked at data from two large clinical trials of the Pfizer-BioNTech and Moderna vaccines.
What they found was that the Pfizer-BioNTech vaccine was more effective at inducing an immune response against the SARS-CoV-2 virus than the Moderna vaccine.
Specifically, they found that the Pfizer-BioNTech vaccine was more effective at inducing neutralizing antibodies, which are the key to protecting against infection.
The findings from this study are significant because they suggest that the Pfizer-BioNTech vaccine is more effective at protecting against SARS-CoV-2 than the Moderna vaccine.
This is important information for people who are considering which vaccine to get, as well as for public health officials who are making decisions about vaccine distribution.
The findings from this study provide new insight into the key differences in immune response to SARS-CoV-2 vaccines and will help to inform decision-making about which vaccine to get.