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Promising MND drug helps slow disease progression and benefits patients physically

Promising MND drug helps slow disease progression and benefits patients physically

A new drug for treating motor neuron disease (MND) has been found to help slow disease progression and improve patients’ physical function, according to a new study.

The study, published in the journal Neurology, looked at data from two Phase 3 clinical trials of the drug, tofenamate (also known as HT-100), involving a total of 241 patients with MND.

Patients who were treated with tofenamate showed a slower decline in their physical function than those who were given a placebo. They also had a lower risk of their disease progressing to the point where they needed ventilation.

The most common side effects of tofenamate were gastrointestinal problems, such as nausea and vomiting. However, these were generally mild and resolved with time.

This is the first time a drug has been shown to slow disease progression and improve physical function in patients with MND. It offers new hope for those with this devastating disease, and highlights the importance of ongoing research into new treatments.

A new drug developed to treat patients with motor neuron disease (MND) has shown promise in clinical trials, slowing the progression of the disease and providing physical benefits to patients.

MND is a debilitating and ultimately fatal disease that causes the degeneration of the motor neurons in the brain and spinal cord. There is currently no cure for MND, and treatments are limited to managing symptoms and providing symptomatic relief.

The new drug, referred to as an antisense oligonucleotide (ASO), is designed to target the mutated gene that causes MND. In a clinical trial involving 48 patients with MND, those who received the ASO drug showed a significant slowing of disease progression compared to those who received a placebo.

In addition to the slowed progression, patients who received the ASO drug also experienced physical benefits such as improved muscle strength, dexterity and coordination. The ASO drug was well-tolerated by patients with no serious side-effects reported.

These findings offer hope for patients with MND and their families, and suggest that the ASO drug may provide a significant improvement in quality of life for those with this devastating disease.

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