Epigenetics is the study of changes in gene expression that are not due to changes in the DNA sequence. Epigenetic mechanisms can silence genes by recruiting chromatin remodeling complexes that compact the DNA and make it inaccessible to the transcription machinery. Alternatively, epigenetic mechanisms can activate genes by recruiting histone modifying complexes that loosen the DNA and make it accessible to the transcription machinery.
The guardian of the (epi-)genome is a metaphor for the role of epigenetic mechanisms in maintaining the stability of the genome. Epigenetic mechanisms silence genes that are not needed in a particular cell type or at a particular stage of development. These silenced genes are usually harmless, but they can become activated if the epigenetic mechanisms that keep them silent are disrupted. When this happens, the genes can cause disease.
The guardian of the (epi-)genome is a metaphor for the role of epigenetic mechanisms in maintaining the stability of the genome. Epigenetic mechanisms silence genes that are not needed in a particular cell type or at a particular stage of development. These silenced genes are usually harmless, but they can become activated if the epigenetic mechanisms that keep them silent are disrupted. When this happens, the genes can cause disease.
Epigenetic mechanisms are essential for normal development and function of cells and tissues. Disruptions of epigenetic mechanisms have been implicated in a wide variety of diseases, including cancer, neurological disorders, and immune disorders.
The field of epigenetics is relatively new, and there is much still to be learned about the role of epigenetic mechanisms in health and disease. However, the potential implications of epigenetics are vast, and the field is rapidly expanding. The guardian of the (epi-)genome is an important metaphor for the role of epigenetic mechanisms in maintaining the stability of the genome and protecting our health.
The cell is the basic unit of life, and all organisms are composed of one or more cells. The human body, for example, is made up of trillions of cells. Cells are so important because they are the building blocks of life. All the functions of the human body, from breathing to thinking, are carried out by cells.
Cells are constantly dividing to make more cells. This happens during growth and repair. When a cell divide
